Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Francisco Bay Area

Best American Restaurants in Mission Bay / South Beach

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Award-winning
Accessibility

145 restaurants available nearby

A photo of House of Prime Rib restaurant
4.8
Exceptional(16011)
Price: Very Expensive
• American • Civic Center / Hayes Valley / Van Ness
Booked 197 times today
House of Prime Rib in San Francisco is a beacon of authentic American cuisine, renowned for its "iconic" status and exceptional prime rib. With 62 years of unwavering dedication, it’s no surprise that this establishment garners glowing praise from loyal patrons who rave about its "festive" atmosphere and "superb" service. Guests continually highlight the "delicious" prime rib, which is described as "massive" and "perfectly cooked," making every visit a memorable experience. The lively ambiance and the meticulous attention from the staff ensure that every meal feels like a special occasion. Truly, House of Prime Rib offers a quintessential American dining experience.
A photo of The Palm Court at RH San Francisco restaurant
4.8
Exceptional(1850)
Price: Very Expensive
• American • Potrero Hill / Dogpatch
Booked 111 times today
The Palm Court is located in RH San Francisco's Gallery at the Historic Bethlehem Steel Building. Recalling the distinctive glamour of San Francisco's Gilded Age, the stunning statement space is sheathed in Italian Calacatta gold marble and features a cascading center fountain, towering Medjool date palms and glimmering chandeliers. Adjacent to the restaurant, two luminous wine bars offer exceptional wines and Champagnes from around the world.For group dining inquiries, please email: sfhospitality@rh.com
A photo of Miller & Lux restaurant
4.8
Exceptional(1223)
Price: Very Expensive
• American • Mission Bay / South Beach
Booked 25 times today
Miller & Lux, nestled in the vibrant Mission Bay area of San Francisco, is a shining beacon of Contemporary American cuisine. With renowned chef Tyler Florence at the helm, this modern American steakhouse artfully blends sophistication with comfort. The restaurant is celebrated for its "delicious steaks" and "incredible Dover sole," showcasing a commitment to sourcing the highest-quality meats and sustainable seafood. Guests rave about the "outstanding service" and the "spectacular setting," making it not just a meal but a memorable experience. Whether enjoying the "table-side Caesar salad" or indulging in the "Michelin-rated burger," every dish promises innovation and authenticity in Contemporary American dining.
A photo of The Rotunda at Neiman Marcus - San Francisco restaurant
4.7
Exceptional(6228)
Price: Expensive
• American • Downtown / Union Square
Booked 89 times today
The Rotunda at Neiman Marcus in San Francisco is a shining example of exquisite American cuisine, offering a dining experience that combines tradition and elegance. Nestled in the heart of Union Square, this iconic venue is beloved for its "excellent service" and "delicious food," consistently leaving diners "extremely satisfied." The Rotunda's menu is celebrated for its innovative takes on American classics, like the "wonderful French 75 cocktail and lobster club sandwich." The chic setting, complete with beautiful views and festive decorations, enhances the atmosphere, making it a "must-visit" destination, especially during the holiday season. Experience the quintessential American dining delight at The Rotunda!
A photo of Wayfare Tavern restaurant
4.6
Exceptional(7873)
Price: Moderate
• American • Financial District / Embarcadero
Booked 83 times today
Wayfare Tavern, nestled in San Francisco's bustling Financial District, stands as a beacon of exemplary Contemporary American cuisine. Chef Tyler Florence masterfully crafts dishes that transport diners to an era of authentic American flavors inspired by the early 20th century. The restaurant is celebrated for its "impeccably delicious" offerings, with standout dishes like the renowned "Mary’s Fried Chicken" and "deviled eggs" that leave patrons raving. The vibrant yet cozy Victorian ambiance complements the culinary delights, making it perfect for any occasion. With "phenomenal" service and a dedication to quality, Wayfare Tavern is a must-visit destination for food enthusiasts.
A photo of Shelby's Rooftop restaurant
4.4
Awesome(341)
Price: Very Expensive
• American • SOMA
Booked 37 times today
Shelby's Rooftop in San Francisco offers a top-notch Dining Bar experience that leaves diners raving about its exceptional ambiance and culinary delights. Perched high above the bustling 4th street, it provides breathtaking views that complement its contemporary-chic vibe. Guests adore the "amazing views of the city and bay," while indulging in expertly crafted cocktails and delectable shared plates like tuna tartare and lobster salad. The service is consistently praised, described as "fabulous" and "attentive," ensuring a memorable outing. Whether you're enjoying the lively indoor atmosphere or the cozy outdoor seating, Shelby's Rooftop promises a captivating and flavorful evening that truly stands out.
A photo of Tartine Manufactory - San Francisco restaurant
4.6
Exceptional(1042)
Price: Expensive
• American • Mission District
Booked 25 times today
Tartine Manufactory in San Francisco’s vibrant Mission District is a beacon of authentic American cuisine, celebrated for its mastery of artisanal bread and world-class sourdough pizza. Diners rave about the restaurant’s "outstanding" food and "fantastic" service, emphasizing the quality of its market-driven, seasonal menu. The pizzas, described as "some of the best in the city," showcase a true American culinary flair with unique toppings and a perfect crust. The atmosphere is equally inviting, with a "lovely, airy space" and a laid-back vibe that makes every visit a special occasion. Tartine Manufactory is a must-visit for anyone craving genuine American flavors.
A photo of Boulevard restaurant
4.8
Exceptional(9151)
Price: Very Expensive
• American • Financial District / Embarcadero
Booked 65 times today
Boulevard, located in San Francisco's vibrant Financial District, offers an exceptional dining experience that effortlessly blends Contemporary French and American cuisine. Guests rave about the "unbelievably delicious" dishes crafted with the "finest and freshest ingredients," beautifully presented and plated with elegance. The prix fixe menu offers a "multitude of choices," allowing diners to explore a variety of flavors. The restaurant's ambience is "stunningly beautiful," especially during the holiday season, making every meal memorable and festive. With top-notch service and a thoughtfully curated menu, Boulevard stands out as a must-visit destination for those seeking high-quality and authentic culinary delights.
A photo of State Bird Provisions restaurant
4.7
Exceptional(3318)
Price: Very Expensive
• American • Western Addition
Booked 94 times today
State Bird Provisions in Western Addition, San Francisco, offers an extraordinary American dining experience that truly stands out. Known for its inventive "dim sum" style service, this restaurant presents a creative twist on classic American flavors. Diners rave about the "delicious, innovative, and surprising" small dishes that keep the experience fresh and exciting. With impeccable service and a lively atmosphere, patrons find themselves returning for more. The signature quail dish and the adventurous blue corn-pepita pancakes with braised bacon and coffee butter are must-tries. As one enthusiastic diner put it, "Every dish was like culinary viagra," making this a must-visit for any American cuisine enthusiast.
A photo of Angler San Francisco restaurant
4.7
Exceptional(297)
Price: Very Expensive
• American • Financial District / Embarcadero
Booked 61 times today
Angler San Francisco, a Michelin-starred gem nestled on the Embarcadero waterfront, offers a seafood experience that truly stands out. With a focus on fresh, seasonal ingredients, each dish is meticulously crafted by Chef de Cuisine Joe Hou, ensuring every bite is a "revelation." Diners rave about the "perfectly prepared" sea bream and "incredible" embered oysters, praising the restaurant's commitment to quality. The ambiance complements the exquisite flavors, with a warm décor and stunning views of the San Francisco Bay. Angler's seafood is not just a meal; it's an "absolutely stunning dining experience" that leaves patrons eager to return.

How is content generated

See what locals rave about

From verified diners like you
From verified diners like you
  • OpenTable Diner
    San Francisco Bay Area •1 review
    5.0
    Dined 2 days ago
    ALWAYS A GREAT EXPERIENCE! Prime Rib is so good like no other! Staff is awesome as always. We love coming back here
    More info
    House of Prime RibPrice: Very Expensive• Steak• Civic Center / Hayes Valley / Van Ness
    4.8
  • lisaVIP
    San Francisco Bay Area •6 reviews
    5.0
    Dined 5 days ago
    Great food (burger, tuna tartare, and truffle fries) and wonderful ambiance. Love this place!!
    More info
    The Rotunda at Neiman Marcus - San FranciscoPrice: Expensive• Contemporary American• Downtown / Union Square
    4.7
  • Clayton
    San Francisco Bay Area •1 review
    5.0
    Dined 6 days ago
    It was an amazing experience, beautiful restaurant, outstanding staff, and food was amazing.
    More info
    The Palm Court at RH San FranciscoPrice: Very Expensive• American• Potrero Hill / Dogpatch
    4.8
  • RobertVIP
    Pittsburgh / Western PA •9 reviews
    5.0
    Dined 7 days ago
    Excellent pizza and atmosphere. Also had a kale Caeser salad that wA delicious
    More info
    Tartine Manufactory - San FranciscoPrice: Expensive• Pizzeria• Mission District
    4.6
  • Kie
    San Francisco Bay Area •1 review
    4.0
    Dined on Mar 4, 2025
    Our first visit to this Michelin star restaurant Miller and Lux was an intriguing introduction to upscale dining. From the moment we walked in, the elegant ambiance set the stage for an evening of culinary exploration. We sampled a selection of dishes that truly highlighted the chef’s skill. The Tomahawk steak was a standout—perfectly cooked and bursting with rich, savory flavors that hinted at careful seasoning and precision in technique. The truffle mac and cheese was delightfully creamy and comforting, a modern twist on a classic dish that left us craving another bite. The salad provided a refreshing contrast with its crisp, vibrant ingredients, made tableside, while the deviled eggs were a playful yet sophisticated nod to traditional flavors, elevated with subtle, unexpected accents. Service throughout the meal was friendly and attentive, though it didn’t quite reach the impeccable standards often associated with Michelin star dining. The staff maintained a warm and polite demeanor, but there were moments when the level of personalized attention could have been sharper. As expected with a Michelin star establishment, the cost was on the higher end. While the prices reflect the quality of the ingredients and the artistry of the presentation, it’s important for diners to be aware that this is a premium dining experience. In summary, despite the service falling just short of stellar, the exceptional food quality and creative dishes made this first Michelin star experience truly memorable. For those willing to indulge in a high-end culinary adventure, Miller and Lux offers a gratifying taste of innovative cuisine and refined flavors.
    More info
    Miller & LuxPrice: Very Expensive• Steakhouse• Mission Bay / South Beach
    4.8

Discover best American restaurants in Mission Bay / South Beach

Discover the vibrant American dining scene in San Francisco's Mission Bay / South Beach area, where culinary delights await at every turn. This neighborhood is renowned for its eclectic mix of restaurants that cater to lovers of American cuisine, offering everything from classic comfort foods to innovative culinary creations. Each establishment reflects a commitment to quality, featuring locally sourced ingredients and expertly crafted dishes that highlight the best of American cooking. In this area, diners can expect a variety of settings, from casual eateries to upscale dining experiences, each providing a unique atmosphere that complements the food. The dining scene here is a testament to San Francisco's diverse and dynamic culture, making it a must-visit destination for food enthusiasts. Whether you're craving a gourmet burger, artisanal cheeses, or a fine dining experience, the Mission Bay / South Beach neighborhood promises an exceptional culinary journey. With a focus on creating a memorable dining experience, these restaurants not only offer exquisite meals but also emphasize warm hospitality and attentive service. This makes each visit not just a meal, but a delightful event that's sure to leave a lasting impression.

  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo