Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Hot Spot Restaurants in Medical Center

Price
Cuisine
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Accessibility

18 restaurants available nearby

A photo of Perry's Steakhouse & Grille - San Antonio restaurant
4.6
Exceptional(9504)
Price: Expensive
• Steakhouse • La Cantera
Booked 80 times today
Located in La Cantera, Perry’s is a great place to spend an evening in The River City. Our popular Bar 79® presents floor-to-ceiling windows with an optional open-air lounge experience and expansive views overlooking local shops. Plus, the spacious, open design gives you the chance to catch glimpses of the chef as he crafts your favorite dishes — adding to the fresh, familiar atmosphere.
A photo of J-Prime Steakhouse San Antonio restaurant
4.8
Exceptional(4399)
Price: Very Expensive
• Steakhouse • North San Antonio
Booked 65 times today
J-Prime Steakhouse in San Antonio is a hot spot. It's been named one of the top 100 most romantic restaurants in America, and diners rave about the excellent service, ambiance, and mouthwatering dishes. From prime cuts of USDA Prime beef to free-range chicken and sustainable seafood, the food is consistently praised. The service is top-notch, and the atmosphere is perfect for a special occasion or just a night out. As one reviewer said, 'this is our go to restaurant for special occasions and it does not disappoint.'
A photo of Chama Gaucha - San Antonio restaurant
4.9
Exceptional(6620)
Price: Very Expensive
• Brazilian Steakhouse • Stone Oak
Booked 97 times today
Welcome to Chama Gaucha Brazilian Steakhouse – where the ultimate dining experience awaits! Indulge your senses in a culinary journey like no other, as we offer an authentic taste of Brazil with our prime cut meats and unwavering commitment to superior service. Our expert gauchos skillfully carve an array of succulent, mouthwatering cuts right at your table, allowing you to savor the flavors and tenderness with every bite.But it's not just the extraordinary dishes that set us apart; it's the service that elevates your visit to unforgettable heights. Our attentive and knowledgeable staff are committed to ensuring that every moment of your dining experience is nothing short of exceptional.Whether you're celebrating a special occasion, enjoying a night out with friends, or simply seeking an extraordinary meal, Chama Gaucha promises to elevate your dining experience to new heights.
A photo of Supper restaurant
4.6
Exceptional(3203)
Price: Expensive
• Contemporary American • Downtown
Booked 46 times today
Supper is a hot spot in San Antonio due to its outstanding food and service. Reviews rave about the 'unique and delicious' menu, with the 'ambiance and location being perfect'. The service is also consistently praised for being friendly and attentive. The restaurant is also lauded for its 'great atmosphere', making it a popular choice for dining and socialising.
A photo of Eddie V’s – Wildfish – San Antonio restaurant
4.8
Exceptional(6735)
Price: Very Expensive
• Seafood • North San Antonio
Booked 50 times today
Eddie V's Prime Seafood is a luxury dining destination known for the seafood flown in from pristine waters around the world, as well as its premium hand-carved steaks. Dishes are artistically prepared and feature an ever-changing array of seasonal seafood, along with critically acclaimed prime center-cut steaks broiled to perfection. The restaurant's award-wining wine list, which has been recognized by Wine Spectator, has more than 300 wines curated by Eddie V's very own Advanced Sommelier. In the V Lounge, guests can sip classic creative cocktails and enjoy signature appetizers.
A photo of Boiler House at Pearl restaurant
4.7
Exceptional(2120)
Price: Expensive
• Contemporary Southern • Downtown
Booked 31 times today
Boiler House at Pearl is a true Texas original. Situated in the historic Pearl Brewery complex on the San Antonio River Walk, this wine-centric restaurant occupies the former “boiler house” which powered the adjacent brewery. Lead by Executive Chef Alberto "Beto" Gutierrez, the menu focuses on grilled items from local farms and markets, with a focus on “Texas ranch-style” cuisine. These delicacies are paired with extraordinary wines from around the world (available by the glass, bottle and “to-go”), full bar, live music and a casual yet energetic atmosphere. The unique list of wines boasts some of the lowest prices in the area.The restaurant incorporates various private dining areas suitable for private or corporate functions and an expansive outdoor patio area where guests can enjoy dining alfresco. We can host groups anywhere from 9 up to 290 guests in our unique, flexible private event spaces.
A photo of Biga on the Banks restaurant
4.8
Exceptional(5817)
Price: Very Expensive
• Contemporary American • Downtown
Booked 17 times today
Overlooking the San Antonio River Walk since 2000, Bruce Auden’s Biga on the Banks continues to charm San Antonio foodies and Alamo City visitors with its constantly-changing new American menu featuring the best ingredients South Texas has to offer.It has been said that Bruce Auden has “put San Antonio on the culinary map” but this Chef is just getting started. The Biga menu features fresh caught fish like Mahi Mahi, True American Red Snapper and Ahi Tuna. Main stays on the menu usually include Hill Country Venison and Bandera Quail, Grilled Australian Rack of Lamb and Roasted Bell & Evans Chicken.The dining room is modern with a casual-well informed style of service.The wine list is eclectic and broad with hundreds of labels and the full bar offers craft cocktails.Biga on the Banks has a versatility about it. If you’re looking for a come-as-you-are impromptu bite, a celebratory dinner with family or a working dinner with business colleagues, Biga fits your needs.
A photo of Paesanos - River Walk restaurant
4.5
Awesome(2262)
Price: Moderate
• Italian • Downtown
Booked 76 times today
Paesanos - River Walk is a hot spot for its sophisticated yet relaxed ambiance and delicious Italian cuisine. The restaurant is highly praised for its excellent service and beautiful location on the River Walk. One review notes, 'atmospheric restaurant with good food and attentive staff. Food was actually hot...' Another review highlights the 'beautiful place, great food, great experience, and wonderful atmosphere.' The consistent high ratings for food, service, and ambiance make it a popular choice among locals and visitors.
A photo of Bliss Restaurant restaurant
5.0
Exceptional(5029)
Price: Very Expensive
• Contemporary American • Downtown
Booked 16 times today
Bliss Restaurant is a hot spot for its consistently high-quality service, ambiance, and cuisine. The reviews rave about the 'exceptional' dining experience with a 'cozy ambiance' and 'tasteful decor'. The 'exquisite' and 'imaginative' food along with 'meticulous and friendly' service earns it top marks. Customers frequently return, even bringing out-of-town guests. The 'comfortable, eclectic atmosphere' and 'outstanding service' make it a 'go-to' place for locals and visitors alike.
A photo of Fogo de Chao - San Antonio restaurant
4.3
Awesome(2626)
Price: Moderate
• Brazilian • Downtown
Booked 90 times today
Fogo de Chão is an internationally-renowned steakhouse from Brazil that allows guests to discover what's next at every turn. Founded in Southern Brazil in 1979, Fogo elevates the centuries-old culinary art of churrasco - roasting high-quality cuts of meat over an open flame - into a cultural dining experience of discovery. Please join us in our dining room, in our more casual Bar Fogo, or bring the Fogo Experience to you with Fogo To-Go or Catering. Visit our website to make a reservation or place an order.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • LeslieVIP
    San Antonio •39 reviews
    5.0
    Dined 2 days ago
    Wonderful Valentine’s Day dinner. Service was on point with a great team effort. Our food and wine pairing was delicious. We will definitely put Supper back on our regular dining out rotation.
    More info
    SupperPrice: Expensive• Contemporary American• Downtown
    4.6
  • Joe
    San Antonio •1 review
    5.0
    Dined 3 days ago
    My girl and I celebrated Valentine’s Day and our anniversary here and the experience was nothing short of amazing. We opted for an early dinner to avoid the larger evening crowd and were immediately welcomed by a warm and friendly staff. Our server, Sean, was outstanding—friendly, attentive, and engaging in the best way possible. His energy and service made our dining experience even more enjoyable. We started with the lobster bisque, which was rich, savory, and generously packed with lobster meat. The tuna tartare was equally impressive, featuring a perfect balance of citrus and spice. For the main course, I had the bone-in ribeye and she had the filet mignon paired with crab stuffed shrimp. Every bite was a masterpiece! The seasoning, texture, and presentation were top tier. As frequent diners at J Prime, we have high expectations, and I can confidently say that Eddie V’s is on the same level, if not better, in terms of taste and quality. Adding to the experience, the manager on duty, Mike, stopped by our table for a friendly chat. He shared some interesting history about the restaurant and other local steakhouses, making us feel even more connected to the place. Overall, this was a memorable dining experience, and Eddie V’s has officially earned a spot in our rotation alongside J Prime and Bohanan’s. We’ll definitely be back!
    More info
    Eddie V’s – Wildfish – San AntonioPrice: Very Expensive• Seafood• North San Antonio
    4.8
  • Lena
    San Antonio •5 reviews
    5.0
    Dined 3 days ago
    I’ve been to many brazilian steak houses with my boyfriend trying to experience them all and this one is by far the best in town. Every single item i tried was rich and flavorful to the point where i was even wanting to try different meats i never have because i knew it would be a waste if i didn’t experience it. If you are going to try any brazilian steak houses make it this one best in texas!
    More info
    Chama Gaucha - San AntonioPrice: Very Expensive• Brazilian Steakhouse• Stone Oak
    4.9
  • Rachel
    San Antonio •5 reviews
    5.0
    Dined 4 days ago
    We were seated promptly at our reservation time. Service was excellent. I noticed a nearby table had an issue with seating, but the staff was very helpful and attentive to getting it resolved. Everyone was focused on good customer service. Food was delicious. Portions were good. Sharable sides can easily feed 3, possibly 4, people. The steaks were ordered from medium to well done, and all of them were cooked perfectly. It is very difficult to find a restaurant that can cook a steak well done without turning it into charcoal, Perry's did it just right. If there is any complaint is that the bananas foster was a little underwhelming. It isn't prepared on a burner and sautéed. It is only flambéed using a butane torch. The rum burns off fairly quickly so the bananas and caramel don't really have time to "cook". It was still delicious but not as delicious as others I've had. Regardless, we definitely recommend Perry's and will be returning.
    More info
    Perry's Steakhouse & Grille - San AntonioPrice: Expensive• Steakhouse• La Cantera
    4.6
  • Lonnie
    Utah •2 reviews
    5.0
    Dined 6 days ago
    We eat at J Prime often. almost always at a bar high top. We were joined by another couple in celebration of my birthday. We had a relaxing and wonderful dinner. Everything from the server to food quality to atmosphere was exceptional. The wives started with cocktails and loved the smokey old fashioned. They each had a slight variation on it, but that alone is a reason for those 2 to enjoy the dinner. Each of us enjoyed a salad (3 beet salads and 1 wedge salad). 3 of us had the kabob and the other had the wagyu steak burger. All of us could not be more pleased with the food. All of this was topped off with the highlight of the meal, a slice of celebration cake. Do not be dissuaded from getting the cake or think that it is something to eat by one. The four of us split the cake slice and didn't finish it. If you are just looking for a late night place for drinks and dessert, you couldn't find a better place to enjoy time in a great atmosphere. If you are looking for the full dinner, the dining room will not disappoint.
    More info
    J-Prime Steakhouse San AntonioPrice: Very Expensive• Steakhouse• North San Antonio
    4.8
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo