Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Diego

Best Southern American Restaurants in Mission Hills

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Award-winning
Accessibility

134 restaurants available nearby

A photo of Old Town Tequila Factory Restaurant & Cantina restaurant
3.9
Excellent(1147)
Price: Moderate
• Southern american • Old Town
Booked 9 times today
Old Town Tequila Factory Restaurant & Cantina is an exceptional spot for authentic American cuisine, offering a delightful experience in the heart of San Diego’s historic Old Town. Diners rave about the "great service" and "fantastic views," making it an ideal destination for both locals and visitors. The rooftop setting adds a unique charm, perfect for a sunset dinner. The Sunday Champagne brunch is a standout, described as "excellent" with "lots to choose from." Whether you're celebrating a special occasion or enjoying a casual meal, the "impeccable service" and delicious food ensure a memorable dining experience.
A photo of Casa De Freds, Tacos y Tequila restaurant
4.5
Awesome(321)
Price: Moderate
• Southern american • Old Town
Booked 4 times today
Casa De Freds, Tacos y Tequila, nestled in the heart of Old Town San Diego, has been the go-to spot for authentic Tex-Mex cuisine since 2001. This vibrant restaurant enchants diners with its "amazing tacos and appetizers" and "outstanding service." What truly sets Casa De Freds apart is its dedication to "quality food" made from fresh, high-quality ingredients, ensuring every bite is bursting with Baja-infused flavors. Guests rave about the "pure pleasure" of dining in their dog-friendly outdoor patio, making it a delightful experience for all. Whether you're a local or just visiting, Casa De Freds promises a festive and flavorful Tex-Mex feast!
A photo of Herb & Wood restaurant
4.7
Exceptional(6491)
Price: Expensive
• Southern american • Little Italy
Booked 87 times today
Herb & Wood in San Diego's vibrant Little Italy is a shining example of exquisite American cuisine. Celebrated Chef Brian Malarkey crafts a menu that elevates rustic, wood-fired dishes, blending Mediterranean flair with California's commitment to seasonality and sustainability. Diners rave about the "incredible dinner" experience, showcasing "amazing, flavorful food" and "outstanding service." The ambiance is described as "beautiful" and "welcoming," making every visit memorable. Signature dishes like the pork belly and filet mignon are praised for their exceptional taste. Whether you're celebrating a special occasion or enjoying a night out, Herb & Wood promises a "truly memorable culinary experience."
A photo of Ironside Fish & Oyster restaurant
4.5
Awesome(4565)
Price: Moderate
• Southern american • Little Italy
Booked 126 times today
Ironside Fish & Oyster in San Diego's Little Italy is a quintessential hotspot for authentic American cuisine, seamlessly blending traditional and contemporary flavors. This gem pays homage to its roots in the fishing industry with a mouthwatering menu that features renowned dishes such as the lobster roll and clam chowder, praised for being “chock full of clams.” The vibrant atmosphere and top-notch service are frequently highlighted in reviews, with one diner noting the “excellent experience, food, and ambience.” With a stellar raw bar and an enticing happy hour, Ironside promises a “delightful experience” that diners find irresistible.
A photo of Kettner Exchange restaurant
4.7
Exceptional(1371)
Price: Expensive
• Southern american • Little Italy
Booked 83 times today
Kettner Exchange in Little Italy, San Diego, offers an exceptional Asian fusion experience that is both inventive and authentic. Executive Chef Brian Redzikowski’s creations have earned the restaurant a coveted spot on the Michelin Guide's Bib Gourmand list since 2019, showcasing high-quality meals at accessible prices. Diners rave about the "spicy garlic noodles" and "juicy cheeseburger special," underscoring the delightful fusion of flavors. The rooftop patio with stunning harbor views enhances the dining ambiance, making it perfect for any occasion. Guests frequently praise the "stellar service" and "amazing cocktails," solidifying Kettner Exchange as a must-visit destination for Asian cuisine enthusiasts.
A photo of The Henry - Coronado restaurant
4.8
Exceptional(2495)
Price: Moderate
• Southern american • Coronado
Booked 164 times today
The Henry - Coronado is a standout destination for exquisite Cocktail Bar cuisine, offering a vibrant and lively atmosphere that feels like a second home. Situated in the heart of Coronado, it features an inviting bar where "creative cocktails are crafted to perfection," ensuring a delightful experience with every visit. Patrons rave about the "outstanding service" and "lively vibe," making it an ideal spot for social gatherings or unwinding after a long day. Whether you're enjoying a holiday drink or a classic concoction, the bar at The Henry ensures a memorable and authentic cocktail experience that keeps guests coming back for more.
A photo of CUCINA urbana restaurant
4.8
Exceptional(7117)
Price: Moderate
• Southern american • Banker's Hill
Booked 56 times today
CUCINA urbana in Banker's Hill, San Diego, offers an exceptional American dining experience with a California-inspired twist. Renowned for its "amazing food and ambience," this restaurant seamlessly blends comfort with contemporary flair, creating a warm yet stylish environment. Diners rave about the "fantastic food and service," particularly highlighting the exquisite pasta and woodfire pizzas that are "second to none." The restaurant's wine program is a standout feature, offering an impressive selection that perfectly complements the menu. With attentive staff and a lively atmosphere, CUCINA urbana is the perfect spot for celebrating life events or enjoying a memorable meal.
A photo of Great Maple San Diego restaurant
4.8
Exceptional(4401)
Price: Moderate
• Southern american • Hillcrest
Booked 116 times today
Great Maple San Diego, nestled in the vibrant neighborhood of Hillcrest, is a beacon of excellence in Contemporary American cuisine. This modern eatery is celebrated for its "outstanding" food and "exceptional" service, making it a favorite destination for brunch, lunch, and dinner. Diners rave about the delightful maple bacon donuts and "delectable" brisket hash, highlighting the creative use of fresh, local ingredients. Reviewers consistently praise the "huge portions" and "fantastic flavors," ensuring no one leaves hungry. With its inviting atmosphere and "friendly" staff, Great Maple offers a truly authentic and memorable dining experience that captures the essence of Contemporary American cuisine.
A photo of Parc Bistro-Brasserie restaurant
4.8
Exceptional(3141)
Price: Moderate
• Southern american • Banker's Hill
Booked 42 times today
Parc Bistro-Brasserie, nestled in the vibrant neighborhood of Banker's Hill in San Diego, is a hidden gem that has earned its place among OpenTable's "100 Best Neighborhood Gems in America for 2021." This charming bistro not only excels in French cuisine but also offers a delightful blend of American flavors, making it a standout choice for those seeking authentic American fare. Diners rave about the "amazing experience" and "excellent food and great service" that make every visit memorable. With a cozy ambiance and a menu that promises both tradition and innovation, Parc Bistro-Brasserie is a must-visit for anyone craving American culinary excellence.
A photo of Farmer's Bottega Restaurant restaurant
4.7
Exceptional(1606)
Price: Moderate
• Southern american • Mission Hills
Booked 28 times today
Farmer's Bottega in Mission Hills, San Diego, offers an exquisite French culinary experience that effortlessly combines authenticity with farm-to-table freshness. Diners rave about the "wonderful dining experience," highlighting the chef’s dedication to using locally sourced ingredients that bring the vibrant flavors of French cuisine to life. Whether indulging in the tender duck gnocchi or savoring the perfectly prepared Cacio E Pepe, each dish is a celebration of French culinary artistry. The charming ambiance, complemented by a beautiful outdoor patio, creates the ideal setting for an unforgettable meal. With exceptional service and a menu brimming with delightful options, this restaurant truly stands out as a neighborhood gem.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo