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Best Seafood Restaurants in Medical Center

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28 restaurants available nearby

A photo of Myron's at Alon Town Center restaurant
1. Myron's at Alon Town Center
4.9
Exceptional(4652)
Price: Expensive
• Seafood • North San Antonio
Booked 25 times today
Myron’s Prime Steak House in North San Antonio is a culinary gem renowned for its exceptional seafood offerings. Nestled in the Alon Towne Centre, Myron’s delights seafood enthusiasts with dishes that consistently exceed expectations. Patrons rave about the freshness and quality of the seafood, with reviews highlighting the "perfectly cooked" sea bass and "outstanding" grilled shrimp. The restaurant's commitment to excellence is evident, as one diner praised, "Always a great place to get fresh meat and seafood and great service." Myron’s not only promises a delightful dining atmosphere but also ensures each seafood dish is crafted to perfection, making every visit memorable.
A photo of Red Lobster - San Antonio - NW Loop 410 restaurant
2. Red Lobster - San Antonio - NW Loop 410
4.4
Awesome(15)
Price: Moderate
• Seafood • North San Antonio
Booked 1 time today
Elevate your day at Red Lobster, where fun meets fancy and every meal is a celebration. Whether you’re marking a special occasion or treating yourself or your crew, Red Lobster is the perfect place to enjoy all your seafood favorites. Dive into our signature shrimp, wild caught lobster and crab, and more. Plus, a variety of fish and popular non-seafood items like our Cajun Chicken Linguini Alfredo. Looking for a showstopper? Create Your Own Ultimate Feast or select a Live Maine Lobster straight from the tank. Or explore our Daily Deals with a different special available each weekday at a price you’ll love. Toast the day with Signature Cocktails including Lobster Punch and Main Deck Margarita Flights to make any moment feel festive. You won’t want to miss our newest menu items or special promotions like Lobsterfest and Crabfest. Reserve online today. Group Dining, To Go, or Catering options. For parties of 11+, please call.
A photo of Landry's Seafood House - San Antonio restaurant
3. Landry's Seafood House - San Antonio
4.5
Awesome(2597)
Price: Moderate
• Seafood • Downtown
Booked 30 times today
Landry's Seafood House in Downtown San Antonio not only captivates with its Gulf Coast charm but also surprises with its exceptional Steak cuisine. Nestled on the picturesque San Antonio Riverwalk, this spot offers more than just stunning views—it offers a steak that could very well be the best you’ve had in a long time. One diner raved, “The food was delicious. It was the best steak I had in a long time.” At Landry's, every steak is a work of art, masterfully prepared and served with the kind of warm, attentive service that makes every meal memorable. Whether you're there for a romantic date or a family gathering, the steak at Landry's promises to be a highlight of your dining experience.
A photo of Eddie V’s – Wildfish – San Antonio restaurant
4. Eddie V’s – Wildfish – San Antonio
4.8
Exceptional(6647)
Price: Very Expensive
• Seafood • North San Antonio
Booked 80 times today
Eddie V’s – Wildfish in North San Antonio is a beacon of Steakhouse cuisine excellence, consistently delivering "top-notch" dining experiences. This luxurious destination is renowned for its "critically acclaimed prime center-cut steaks broiled to perfection," making every meal a carnivorous delight. Diners rave about the quality, with reviews highlighting that the steaks are "always cooked to perfection." The ambiance, service, and attention to detail, such as "roses and a card awaited us at the table," elevate each visit, making Eddie V's the go-to spot for special occasions. Whether you're celebrating a milestone or seeking a superb steak dinner, Eddie V's promises an "exquisite dining experience" that's simply unmatched in San Antonio.
A photo of Dean's Steak & Seafood restaurant
5. Dean's Steak & Seafood
4.6
Exceptional(204)
Price: Very Expensive
• Seafood • Downtown
Booked 38 times today
At Dean's Steak & Seafood in Downtown San Antonio, the steak experience is truly unparalleled. Nestled in a historic 19th-century schoolhouse, Dean's offers a selection of prime steaks, including A5 Japanese and Texas Wagyu, celebrated for their succulent and flavorful qualities. Patrons rave about the authenticity and quality of the offerings, with one diner describing their Wagyu as "delicious and fun at the same time," and steaks that were "cooked perfectly" and "tender and flavorful." Whether you're a local or visiting, Dean's is the go-to destination for steak aficionados seeking a top-tier dining experience in a unique, atmospheric setting.
A photo of Bohanan's Prime Steaks and Seafood restaurant
6. Bohanan's Prime Steaks and Seafood
4.8
Exceptional(8259)
Price: Very Expensive
• Seafood • Downtown
Booked 56 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio is a gastronomic landmark where the allure of tender, prime beef and fresh seafood create a perfect dining experience. Known for its mesquite-grilled steaks like the "spectacular" Akaushi beef, Bohanan’s also boasts a AAA Four Diamond rating and a Wine Spectator’s Best of Award of Excellence. Diners rave about the "perfect steak doneness" and "spectacular table-side desserts flambé." The ambiance, set in a historic building near the River Walk, adds to its charm, making every visit memorable. It’s no wonder guests say, "Bohanan’s is consistently the best service in the city," making it a must-visit for anyone seeking the quintessential steakhouse experience.
A photo of Chart House Restaurant - Tower of the Americas restaurant
7. Chart House Restaurant - Tower of the Americas
4.5
Awesome(16570)
Price: Moderate
• Seafood • Downtown
Booked 165 times today
Dine in the heart of Downtown San Antonio at Chart House Restaurant, a haven of American cuisine that promises more than just a meal. Celebrated for both its culinary prowess and enchanting views, Chart House offers an array of finely-crafted American dishes, from fresh fish specialties to the sumptuous slow-roasted prime rib. Guests rave about the "delicious food and great service," with highlights including the "best key lime pie ever" and an original Hot Chocolate Lava Cake that perfectly concludes a memorable dining experience. Whether it's the stunning city vistas or the "exceptional service," Chart House provides a dining experience that consistently delights and surprises, making it a must-visit for locals and tourists alike.
A photo of Rebelle restaurant
8. Rebelle
4.6
Exceptional(2385)
Price: Moderate
• Seafood • Downtown
Booked 21 times today
Rebelle, located in the heart of downtown San Antonio within the prestigious St. Anthony Hotel, stands out not only as a top seafood destination but also as a paradise for steak lovers. While renowned for its seafood, Rebelle's signature cast-iron Ribeye and Filet Mignon truly elevate the steak dining experience. Critics and patrons alike rave about the quality of their steaks, highlighting the "excellent" food and ambiance. As one reviewer exclaimed, "Food was seasoned very well and cooked to perfection." Whether you're a local or visiting, make sure to reserve a spot at Rebelle to indulge in some of the finest steaks San Antonio has to offer, complemented by impeccable service and a contemporary setting.
A photo of Perry's Steakhouse & Grille - San Antonio restaurant
9. Perry's Steakhouse & Grille - San Antonio
4.7
Exceptional(9344)
Price: Expensive
• Seafood • La Cantera
Booked 95 times today
Perry's Steakhouse & Grille in San Antonio's La Cantera neighborhood is a beacon of American cuisine, offering a genuine taste of culinary excellence. Known for its iconic, "Texas-sized" pork chops and an array of well-crafted dishes, Perry's provides a dining experience that leaves patrons raving about its quality and authenticity. As one diner exclaims, the pork chops are "always amazing," and another recommends not missing the Friday lunch special for a fulfilling experience. The ambiance, including views from Bar 79® and the attentive service, complements the delicious offerings, making Perry's a must-visit for those seeking the heart and soul of American dining in The River City.
A photo of BLÜ Prime Steakhouse restaurant
10. BLÜ Prime Steakhouse
4.7
Exceptional(623)
Price: Very Expensive
• Seafood • North Central
Booked 25 times today
BLÜ Prime Steakhouse in North Central, San Antonio, is a beacon of culinary excellence, particularly noted for its transformative steak cuisine. Diners consistently rave about the "outstanding flavorful food" and the "exceptional taste ribeye." What sets BLÜ apart is its in-house dry age steak program, ensuring each cut is perfectly aged for peak flavor and tenderness. One patron highlighted, "The steak was one of the most tender and flavorful filets I’ve ever had." The restaurant's commitment to quality is unmatched, with a five-star wine list and a craft cocktail bar to complement your meal. BLÜ Prime Steakhouse is not just a meal; it’s a prestigious dining experience where each steak served is a masterpiece of culinary craft.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Sarah
    San Antonio •2 reviews
    5.0
    Dined today
    Our table had the sashimi and calamari as appetizers. Lobster bisque and then each couple split the special which was two medallions and jumbo shrimp. Chocolate cake for dessert. Everything was wonderful, as always. Service was great as well. We will be back.
    More info
    Eddie V’s – Wildfish – San AntonioPrice: Very Expensive• Seafood• North San Antonio
    •
    4.8
  • OpenTable Diner
    San Antonio •3 reviews
    5.0
    Dined 4 days ago
    Food was great! Temperature in restaurant was cold, A/C blowing when it was cool outside.
    More info
    Landry's Seafood House - San AntonioPrice: Moderate• Seafood• Downtown
    •
    4.5
  • JamesVIP
    San Antonio •28 reviews
    5.0
    Dined 6 days ago
    Great Business Dinner Experience. We were able to get a small room, which was perfect for 10 people. The wait staff was "just attentive enough". They were IMMEDIATELY there when you wanted them and otherwise stayed out. The food was fantastic, (our group have variety of appetizers and entrees ranging from Fish to Pork Chops). The deliveries of the different courses was perfectly timed. Our waiter was GREAT! (He made exceptional recommendations and made all my out-of-town guest feel like they were locals. It was an OUTSTANDING evening. In closing, I have been dinning at THIS Myron's for over 10 years and the service there has been consistently exceptional. Whenever I have an important business dinner, I know I can always trust that Myron's will deliver.
    More info
    Myron's at Alon Town CenterPrice: Expensive• Steak• North San Antonio
    •
    4.9
  • MonicaVIP
    San Francisco Bay Area •9 reviews
    5.0
    Dined 6 days ago
    We’re locals so heading downtown for dinner can be a bit of a pain, but this restaurant is absolutely worth it. The service is top notch and the restaurant is beautiful. Most importantly, the food is amazing. We started with the crab cake and hot stone wagyu and I highly recommend both. For entrees, the prime ribeye was one of the best steaks I have ever had, and the halibut was perfectly prepared. Overall, it was a beautiful evening, and an outstanding experience. We will absolutely be back! Pro tip- don’t fill up on the Parker house rolls!!
    More info
    Dean's Steak & SeafoodPrice: Very Expensive• Steak• Downtown
    •
    4.6
  • DDPhD
    San Antonio •33 reviews
    4.0
    Dined on Jan 30, 2022
    Okay for everyday dining. Server had a delightful personality and attitude.
    More info
    Red Lobster - San Antonio - NW Loop 410Price: Moderate• Seafood• North San Antonio
    •
    4.4

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