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Best Southwest American Restaurants in South Portland

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15 restaurants available nearby

A photo of Buffalo Wild Wings - South Portland restaurant
1. Buffalo Wild Wings - South Portland
4.0
Excellent(18)
Price: Moderate
• Mexican • South Portland
Booked 2 times today
Since 1982, Buffalo Wild Wings® (or B-Dubs® as our friends call us) has been the ultimate place to watch the game, have a cold beer and eat some great food. At Buffalo Wild Wings, you can always feel comfortable pulling some tables together with your friends and staying as long as you want.
A photo of Sea Dog Brewing Co. - So. Portland restaurant
2. Sea Dog Brewing Co. - So. Portland
4.3
Awesome(36)
Price: Moderate
• Mexican • Portland
Using only the most superior ingredients in their beer and plates, Sea Dog Brewing Company in South Portland serves up innovative pub fare with an original touch. All beer sold at Sea Dog Brewing Company are hand-crafted, as is the American pub cuisine, adding to the restaurant's authenticity. The restaurant offers ample seating for most party sizes, and boasts a private function room available to reserve for group gatherings. Sea Dog Brewing Company offers a selection of pub comfort favorites like Maine lobster bisque with huge chunks of lobster meat, steak tip poutine, and plenty of shareable appetizers. In addition, the menu features other popular dishes like fish and chips and blackened haddock tacos, as well as vegetarian and gluten free options.The friendly staff at Sea Dog Brewing on Western Avenue in South Portland would love to take care of you while you await your flight at PWM, on your lunch break from work, or for weekend brunch with family and friends!
A photo of David's Restaurant restaurant
3. David's Restaurant
4.7
Exceptional(3857)
Price: Moderate
• Mexican • Portland
Booked 20 times today
David's Restaurant in Portland is a shining example of authentic American cuisine, celebrated for its "delicious meals and warm, friendly service." Located in the heart of the historic arts district, this local favorite enchants with its eclectic decor and energetic ambiance. Diners rave about its inventive twists on classic American dishes, such as the "incredible meatloaf dinner" and "fresh, creatively prepared seafood." Chef David, voted Portland's best chef in 2021, ensures each dish is a masterpiece, offering options for gluten-free, vegetarian, and vegan diners. With consistent praise for both food and service, it's clear why David's is a must-visit destination for American culinary delights.
A photo of Isa Bistro - Portland restaurant
4. Isa Bistro - Portland
4.9
Exceptional(1419)
Price: Expensive
• Mexican • Portland
Booked 27 times today
Isa Bistro in Portland is a delightful gem that masterfully combines the essence of authentic Italian cuisine with a touch of creative flair. With a menu crafted by a James Beard-nominated chef, Isaul Perez, the bistro offers dishes that are both eclectic and seasonally inspired, reflecting the vibrant flavors of Italy. Diners rave about the "exquisite eggplant lasagna" and the "perfectly cooked halibut," showcasing the restaurant's commitment to quality and taste. The cozy, intimate atmosphere, coupled with outstanding service, ensures an unforgettable dining experience. Isa Bistro stands out in Portland as a must-visit destination for anyone craving exceptional Italian cuisine.
A photo of Bird & Co. restaurant
5. Bird & Co.
4.8
Exceptional(282)
Price: Moderate
• Mexican • Portland
Booked 9 times today
We are a neighborhood Taco and Margarita bar. We would love to feed you. Located in the middle of Woodfords Corner, tucked away on the Corner of Deering Ave. and Revere St. Our creative tacos and margaritas use the freshest ingredients and we have something on the menu for everyone. You deserve Tacos.
A photo of Thames Landing restaurant
6. Thames Landing
4.4
Awesome(49)
Price: Expensive
• Mexican • Portland
Booked 4 times today
Thames Landing offers an exquisite seafood experience in the heart of Portland, making it a must-visit for seafood enthusiasts. Known for its modern New England fare, the restaurant delights with dishes like the perfectly seasoned lobster rolls and the mouthwatering mussel appetizer, celebrated for its "most delicious sauce." Diners rave about the "lobster mushroom risotto," describing it as a standout dish that embodies authenticity and fresh, local flavors. With its airy dining room and cozy garden patio, Thames Landing provides not only exceptional seafood but also a welcoming atmosphere, ensuring a memorable meal with every visit.
A photo of REGARDS restaurant
7. REGARDS
4.6
Exceptional(268)
Price: Expensive
• Mexican • Portland
Booked 9 times today
REGARDS, located in the heart of Portland, is a beacon of Contemporary Mexican cuisine, skillfully blending the vibrant flavors of Mexico with the innovative culinary techniques of Los Angeles. Celebrated as one of "The 50 Best New Restaurants of 2022" by Bon Appetit, this dining gem offers an adventurous menu featuring "bright, zippy ceviches" and "plump Argentinian shrimp tacos" that leave diners raving. Guests have lauded the "fascinating flavor" of the mezcal-cured hamachi collar and the inventive use of fresh, local Maine produce. With an array of curated mezcals and tequilas, REGARDS delivers a dining experience that's as unforgettable as it is delicious.
A photo of Eighteen95, at The Portland Regency Hotel & Spa restaurant
8. Eighteen95, at The Portland Regency Hotel & Spa
4.5
Awesome(338)
Price: Moderate
• Mexican • Portland
Booked 2 times today
Eighteen95 at The Portland Regency Hotel & Spa is a shining beacon of Contemporary American cuisine in Portland. This elegant establishment offers a cozy ambiance with its softly lit chandeliers and inviting brick fireplace. Diners rave about the "spectacular service" and "yummy food," making it a must-visit spot for brunch enthusiasts. The menu, featuring delights like Eggs Benedict and malted pancakes with blueberries, is a testament to the quality and authenticity of its Contemporary American offerings. Guests appreciate the "creative breakfast cocktails" and the renowned "John's Bloody Marys." With such glowing reviews, Eighteen95 is truly a gem in the heart of Portland.
A photo of Uno Pizzeria & Grill - S. Portland restaurant
9. Uno Pizzeria & Grill - S. Portland
3.6
Very Good(12)
Price: Moderate
• Mexican • South Portland
Uno draws its identity and inspiration from the artisan heritage of the original Pizzeria Uno in Chicago, IL. Each restaurant still makes their Deep Dish Pizza dough fresh every morning. Our Chicago Thin Crust Pizzas are jam-packed with bold flavors. And our new Detroit Style Pizza, with its square shape, crunchy and crispy cheese-baked edge and light and airy crust, is a new favorite among our guests. We offer pizzas that are perfect for all meat-lovers, vegans, and gluten-free guests alike!Today, we are as passionate about craft beer as we are our pizza. We work with quality brewers to bring you a selection of some of the best national, regional and local craft beers. Nothing goes better together than pizza and beer!Our menu also features UNO favorites like the Shrimp & Crab Dip and Rattlesnake Pasta as well as a variety of other apps and pastas, salads, burgers and sandwiches, and entrees.
A photo of David's 388 restaurant
10. David's 388
4.8
Exceptional(1378)
Price: Expensive
• Mexican • South Portland
Booked 7 times today
David's 388 in South Portland shines as a beacon of Contemporary American cuisine, offering a delightful blend of creative and traditional flavors. This cozy neighborhood haven, crafted "by the Chef, for the Chef," features a dynamic menu that keeps diners returning for more. Its dishes, like the seafood pappardelle and cumin salmon, receive rave reviews for being "absolutely delicious" and "expertly done." The warm and inviting atmosphere, paired with attentive service from staff like Lexi and Faye, makes every visit memorable. David's 388 is a "fantastic experience" where "the food is always spectacular," making it a must-visit for food enthusiasts.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

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