Best Southwest American Restaurants in Little Italy

162 restaurants available nearby

A photo of Ironside Fish & Oyster restaurant

1. Ironside Fish & Oyster

4.4

Price: Moderate

• Mexican • Little Italy

Booked 79 times today

Nestled in the heart of San Diego's vibrant Little Italy, Ironside Fish & Oyster is a gem for seafood enthusiasts. Celebrated for its dedication to the freshest and highest quality seafood, this restaurant has transformed a historic auction house into a bustling seafood haven with an expansive raw bar and open-air culinary hubs. Patrons rave about their "10/10 plump oysters" and assert that the "fish and chips may be the best in San Diego." Not to be missed are their lobster rolls, described as "the best thing I ever had!" With its cool vibe and exceptional service, Ironside Fish & Oyster offers an unforgettable dining experience right by the docks where the city's fishing legacy continues to thrive.

2. Herb & Wood

4.7

Exceptional(6429)

Price: Expensive

• Mexican • Little Italy

Booked 75 times today

Herb & Wood in Little Italy, San Diego, epitomizes the essence of Mediterranean cuisine with a delightful twist of Californian flair. Celebrated Chef Brian Malarkey crafts a menu that transforms simple ingredients into a symphony of flavors, all centered around a wood-fired concept that accentuates each dish's rustic, authentic taste. Reviewers consistently praise the restaurant's vibrant atmosphere and innovative dishes, with one guest exclaiming, "The bone marrow and oyster dish was especially impressive!" and another noting the "swordfish was very fresh and tasty." Herb & Wood not only offers a feast for the taste buds but also a Mediterranean dining experience that is both heartfelt and memorable, making it a culinary jewel in San Diego.

3. Kettner Exchange

4.7

Exceptional(1332)

Price: Expensive

• Mexican • Little Italy

Booked 37 times today

Kettner Exchange in Little Italy, San Diego, is a paragon of Contemporary American cuisine, offering a unique dining experience that reflects the very essence of culinary innovation. With its expansive harbor views from the rooftop patio and the culinary prowess of Executive Chef Brian Redzikowski, the restaurant has consistently wowed diners and critics alike, earning a spot on the Michelin Guide's Bib Gourmand list since 2019. Reviews often highlight the inspired menu, such as one diner’s praise for the “magical” way flavors and textures are combined. Another reviewer raves, “UNBELIEVABLE! THE MOST INCREDIBLE DINING EXPERIENCE OF MY LIFE,” underscoring the exceptional quality and creativity on display. Kettner Exchange's commitment to a thrilling gastronomic journey makes it a must-visit for those seeking the best in Contemporary American fare.

A photo of Crudo Ceviche & Oyster Bar restaurant

4. Crudo Ceviche & Oyster Bar

4.5

Awesome(170)

Price: Moderate

• Mexican • Little Italy

Booked 10 times today

Crudo Ceviche & Oyster Bar in Little Italy, San Diego, stands as a beacon of Contemporary Mexican cuisine with its innovative approach to seafood. Patrons rave about the "best not Italian restaurant in little Italy" where "every piece of fish and seafood is tremendously fresh, tasty, and plenty!" The restaurant’s unique blend of Baja-inspired dishes like the snow crab claws and octopus carpaccio receive glowing accolades for their freshness and beautiful presentation. The ambiance is equally praised, described as "hip, warm" with an "awesome atmosphere." The combination of finely crafted cocktails, attentive service, and an eclectic menu ensures that Crudo Ceviche & Oyster Bar is a must-visit for an authentic and memorable dining experience.

A photo of King & Queen Cantina - San Diego restaurant

5. King & Queen Cantina - San Diego

4.5

Awesome(1173)

Price: Moderate

• Mexican • Little Italy

Booked 11 times today

King & Queen Cantina in Little Italy, San Diego, is a vibrant hotspot where Mexican cuisine meets an electric party atmosphere. Esteemed for its innovative fusion of Latin dishes with Asian flavors, this cantina is a culinary delight. Patrons rave about the "bursting flavors" of their tacos, with one reviewer exclaiming they are the "best Birria tacos I've had outside of Mexico." The restaurant's ambience enhances the dining experience, described as having a "weekend vibe on a Tuesday night." From their famous Margarita flight to the generous portions of uniquely flavored tacos, King & Queen Cantina offers an unforgettable dining experience that keeps locals and visitors alike coming back for more.

6. Coco Maya

4.7

Exceptional(375)

Price: Expensive

• Mexican • Little Italy

Booked 4 times today

Coco Maya in Little Italy, San Diego, is a delightful revelation in Contemporary American cuisine, offering a creative twist on classic American fare. The restaurant's use of a traditional Spanish-style coal-fired Josper oven brings a unique flavor profile to robust, flavorful proteins, setting it apart in a neighborhood rich with culinary offerings. Reviewers rave about the diverse menu, highlighting dishes like the "delicious" short rib pasta and "amazing" skirt steak. The ambiance, enhanced by sweeping views of Little Italy and a vibrant rooftop setting, is consistently praised. It’s not just the food that receives acclaim; the cocktail program, featuring a diverse mezcal and tequila selection, is also a highlight. Visitors describe their dining experience as “unforgettable,” noting the "fun atmosphere" and exceptional service that make Coco Maya a must-visit spot in San Diego.

7. Fisher's

4.0

Excellent(135)

Price: Expensive

• Mexican • Little Italy

Booked 2 times today

Nestled in San Diego's vibrant Little Italy, Fisher's stands out for its exceptional Contemporary Mexican cuisine, masterfully blending traditional flavors with innovative seafood creations. Since its humble beginnings in 1989, Fisher's has captivated diners with dishes that are both "authentic from Mexico City and great spice!” as per one ecstatic review. Guests rave about the "unique flavors" and consider the ceviche among the "best ever had." Fisher's not only promises an unforgettable dining experience with its friendly ambiance and "excellent cocktails," but it also delights with attentive service and a menu that makes every visit a culinary discovery. Whether you're a local or a visitor, Fisher's is highly recommended for anyone looking to enjoy top-notch Contemporary Mexican cuisine right in the heart of San Diego.

8. Petrini's

4.5

Awesome(424)

Price: Moderate

• Mexican • Little Italy

Booked 1 time today

Petrini's in San Diego's vibrant Little Italy is a culinary gem, celebrated for its exceptional American cuisine with a unique twist. This eatery stands out for its dedication to quality and authenticity, drawing diners back time and again. Guests rave about the "delicious and homemade tasting" dishes, highlighting the smoked salmon alfredo and the innovative diablo shrimp as must-tries. The restaurant's atmosphere is consistently praised, with one visitor noting it as a "quiet, quaint, and beautiful eatery with old world recipes." Petrini's commitment to excellence is evident in every dish, making it a top destination for those seeking authentic American flavors in San Diego.

9. Coasterra

4.5

Awesome(7531)

Price: Moderate

• Mexican • Harbor Island

Booked 55 times today

Coasterra stands out as a crown jewel of Seafood cuisine in San Diego, particularly celebrated for its fresh, innovative Mexican flavors right on the waterfront of Harbor Island. Patrons rave about the "spectacular view of the San Diego skyline" while indulging in dishes like the "Blood Orange Scallop Aguachile" and "Ancho Chili Roasted Salmon" which are just a few highlights of their diverse seafood offerings. As one diner exclaims, the seafood is "incredibly fresh and wonderful in flavor," ensuring each meal is an unforgettable experience. Whether you're a local or just visiting, Coasterra offers not only a meal but an experience, complete with "impeccable service" and a setting that makes every dining occasion special.

10. CUCINA urbana

4.7

Exceptional(7085)

Price: Moderate

• Mexican • Banker's Hill

Booked 47 times today

Nestled in the vibrant Bankers Hill neighborhood of San Diego, CUCINA urbana offers a sublime blend of American cuisine with a unique twist. This gem has been delighting patrons since 2009, merging a cozy farmhouse vibe with a modern art installation, making each dining experience both comforting and visually stimulating. The restaurant's dedication to quality is evident, with diners raving about the "stellar" food and "exceptional" service. Highlights include the meatballs with a "spicy" kick and the perfectly cooked rigatoni, not to mention the "spectacular" desserts like tiramisu and limoncello mousse tart. The innovative wine program allows guests to select from a range of both familiar and rare vintages at retail prices, enhancing meals or to enjoy at home. CUCINA urbana isn't just a meal; it's a culinary celebration in the heart of San Diego.

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See what locals rave about

From verified diners like you

J
Julievip
San Diego •35 reviews
5.0
Dined 1 day ago
Very good as always and very pleasant service as always. Highly recommended!!
More info
Blanco Cocina + Cantina - CoronadoPrice: Moderate• Mexican• Coronado
•
4.7
K
Kimvip
Minneapolis - St. Paul •21 reviews
5.0
Dined 1 day ago
Great outdoor area with comfortable seating, strong drinks, and heat lamps. Perfect spot before a visit to the movies or holiday shopping.
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Blanco Cocina + Cantina – Fashion ValleyPrice: Moderate• Mexican• Mission Valley
•
4.8
C
Cheryl
Los Angeles •1 review
5.0
Dined 4 days ago
We chose Fred’s for our dog, Ziggy. The staff were more than accommodating - they are dog lovers and people persons, making us all feel at home. Great food, pure pleasure!
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Casa De Freds, Tacos y TequilaPrice: Moderate• Mexican• Old Town
•
4.4
H
Hans
San Diego •1 review
4.0
Dined on Nov 18, 2024
Always enjoyable! I'm a big fan of the Queso Fundito. Parking can be a challenge, but it is well worth it.
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Ortega's A Mexican BistroPrice: Moderate• Mexican• Hillcrest
•
4.5
C
Cynthia
San Diego •10 reviews
5.0
Dined on Nov 10, 2024
The food was delicious! The drinks were also delicious! Food is moderately priced, but the drinks are quite expensive! Guacamole was plentiful and very tasty! Our server was extremely helpful and personable! First time at blind and we would come again!
More info
Blind BurroPrice: Moderate• Mexican / Southwestern• Downtown
•
4.5

Discover best Mexican / Southwestern restaurants in Little Italy

Discover the vibrant flavors of Mexican cuisine right in the heart of San Diego's Little Italy, a culinary hotspot known for its diverse and robust dining scene. Here, you'll find an array of Mexican restaurants that masterfully blend traditional Latin dishes with unique, local twists. Each establishment offers a distinct experience, from authentic Baja-style seafood at Crudo Ceviche & Oyster Bar to the innovative fusion of Latin and Asian flavors at King & Queen Cantina. Patrons consistently praise the high-quality food, ranging from birria tacos to exquisite ceviche, and commend the excellent service and cozy atmospheres. Whether you’re looking for a lively spot for Happy Hour or a sophisticated setting for a family meal, Little Italy’s Mexican restaurants provide exceptional dining experiences that cater to all tastes. Embrace the rich culinary traditions and modern interpretations of Mexican cuisine in one of San Diego's most charming neighborhoods.

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Best Southwest American Restaurants in Little Italy

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162 restaurants available nearby

1. Ironside Fish & Oyster

2. Herb & Wood

3. Kettner Exchange

4. Crudo Ceviche & Oyster Bar

5. King & Queen Cantina - San Diego

6. Coco Maya

7. Fisher's

8. Petrini's

9. Coasterra

10. CUCINA urbana

See what locals rave about

Discover best Mexican / Southwestern restaurants in Little Italy

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