Best Southwest American Restaurants in W. University / Med Center

184 restaurants available nearby

A photo of Drake's Hollywood - Houston restaurant

1. Drake's Hollywood - Houston

4.6

Exceptional(154)

Price: Very Expensive

• Mexican • Montrose

Booked 51 times today

Drake's Hollywood in Montrose, Houston, is a steak lover's paradise, delivering an unforgettable dining experience with its top-notch cuisine and opulent atmosphere. Patrons rave about the "Hawaiian Crusted Ribeye," a standout dish known for its "super flavorful and extremely tender" meat, which rivals the best steakhouses in Texas. The restaurant's commitment to quality is evident, as one review highlights the ribeye's "perfect crust and precise cooking," making it a must-try for any steak enthusiast. Alongside its celebrated steaks, Drake's Hollywood offers a glamorous Old Hollywood vibe, making each visit not just a meal, but a spectacular event.

2. Milton's

4.7

Exceptional(72)

Price: Expensive

• Mexican • Rice Village

Booked 15 times today

Formerly known as Eau Tour, Milton's is an Italian-American trattoria from the same team that you already know and love! Milton's will feature homemade pastas and wood-fired meats, and an array of craft cocktails made to be enjoyed in our vibrant, revamped space. Opening soon!

3. Rosie Cannonball

4.7

Exceptional(38)

Price: Expensive

• Mexican • Montrose

Booked 31 times today

Rosie Cannonball, nestled in the vibrant Montrose neighborhood of Houston, serves up a delightful slice of Italy with its exquisite Italian cuisine. Patrons rave about the authentically crafted dishes, with the "Cacio e pepe pizza" being heralded as a must-try that is "to die for." The restaurant's commitment to quality is evident, as they skillfully utilize a wood-burning oven to enhance the flavors of their handcrafted pizzas and pastas, ensuring each dish celebrates the essence of Italian cooking. The ambiance is described as "lively and chic," perfect for enjoying the "geeky wine list" that complements the Italian-centric menu. Whether it's the praised "phenomenal presentation" of the food or the "excellent service" that makes every dining experience memorable, Rosie Cannonball is a gem in Houston's culinary scene, consistently impressing with its robust Italian flavors and vibrant atmosphere.

4. Eunice

4.7

Exceptional(2612)

Price: Moderate

• Mexican • Upper Kirby / Shepherd Corridor

Booked 38 times today

Eunice, nestled in the Upper Kirby / Shepherd Corridor of Houston, epitomizes the essence of Contemporary Southern cuisine with its modern Cajun-Creole brasserie flair. Inspired by the childhood flavors of South Louisiana native and Executive Chef Drake Leonards, Eunice artfully blends Gulf Coast ingredients with European techniques. Patrons rave about the "traditional Creole/Cajun fare with modern twists" and celebrate its atmosphere as "just the right blend of elegance and Louisiana fun!" Whether it's the divine cornbread, exceptional gumbo, or the bustling happy hour featuring $1.50 oysters, Eunice delivers an unparalleled dining experience that’s both authentic and innovative. Join the chorus of satisfied diners who insist, "Don't think about it, just go!"

A photo of Clark's Oyster Bar - Houston restaurant

5. Clark's Oyster Bar - Houston

4.8

Exceptional(395)

Price: Expensive

• Mexican • Montrose

Booked 58 times today

Nestled in the bustling Montrose neighborhood of Houston, **Clark's Oyster Bar** is celebrated for its exceptional Seafood offerings, particularly its freshly shucked oysters and delectable lobster rolls. Patrons rave about the "best lobster roll in Houston" and commend the "fresh and well-crafted" seafood that shines through dishes like cioppino and crudo. The restaurant's ambiance, highlighted by a light, nautical theme, complements its culinary delights, making every dining experience remarkable. With glowing reviews such as "Best Oysters in Houston!" and accolades for its knowledgeable service, Clark’s is a must-visit for seafood lovers seeking both freshness and flair in every bite.

6. Balboa Surf Club

4.8

Exceptional(53)

Price: Expensive

• Mexican • Galleria / Uptown

Booked 44 times today

Balboa Surf Club is an upscale American restaurant in the heart of Uptown, Houston, located in Post Oak Plaza. The menu places an emphasis on fresh seafood from around the country, including a curated sushi program, as well as salads, hearty sandwiches, a standout hamburger, and hand-cut steaks.Beverage selections include classic house cocktails, and an extensive yet approachable wine list.The dining room is made up of lush plants, intimate booths as well as a full service bar and lush patio.Balboa is open 7 days a week for both lunch and dinner.

7. Leo's River Oaks

4.6

Exceptional(72)

Price: Very Expensive

• Mexican • River Oaks

Booked 31 times today

Welcome to Leo's River Oaks. We looking forward to seeing you.

A photo of Hudson House - River Oaks restaurant

8. Hudson House - River Oaks

4.7

Exceptional(402)

Price: Moderate

• Mexican • River Oaks

Booked 78 times today

Nestled in the charming River Oaks neighborhood of Houston, Hudson House shines as a beacon of American cuisine, offering a delightful blend of East Coast-inspired, "old-school casual" flair. The restaurant's commitment to quality is evident in its daily-flown oysters and the rave reviews of its "World’s Coldest Martinis." Diners consistently praise the impeccable service and the authentically American dishes like the succulent lobster roll and the pan-seared redfish. As one reviewer exclaimed, "The food is outstanding and the drinks are great. The Bleu Gold martini is a top 10, ice cold." Hudson House - River Oaks not only promises a culinary journey but also delivers an experience that embodies the heart of American dining, making it a must-visit destination for both locals and visitors in Houston.

9. JOEY Uptown

4.6

Exceptional(85)

Price: Moderate

• Mexican • Westside

Booked 128 times today

JOEY Restaurants marries iconic hospitality with a handcrafted, locally and globally-inspired menu from award-winning chefs, to bring an unparalleled guest experience. Instead of just one chef, JOEY has a whole team of celebrated Executive Chefs bringing you an experience you can't get anywhere else. JOEY Uptown, boasts an open concept dining room that spans over 10,288 square feet, including a temperature controlled patio equipped with an outdoor bar. Stylized prints from Texas-based artist Jon Flaming, and animated LED portraits by Julian Opie, bring life and lightness to the entire space. This location fits Houston’s iconic food scene like a glove.

10. Flora

4.8

Exceptional(774)

Price: Moderate

• Mexican • Montrose

Booked 66 times today

Nestled in the scenic Montrose neighborhood of Houston, Flora delights diners with its innovative approach to Traditional Mexican cuisine. Celebrated for its beautiful "glass treehouse" ambiance and meticulous attention to high-quality, organic ingredients, Flora offers a "top-notch culinary experience" that is both familiar and freshly inventive. Guests rave about the "best fajitas I've ever had" and "amazing churros," highlighting the restaurant's commitment to authenticity with a modern twist. The vibrant setting, complete with live music and a stunning terrace, complements the dining experience, making Flora a beloved destination for lovers of genuine Mexican flavors in Texas.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you

N
NANCY DVIP
Houston •53 reviews
5.0
Dined 2 days ago
One of our favorites. Guacamole is the best in town & the margaritas are fabulous. Over the years, we’ve sampled just about everything on the menu & it’s all delicious. Be sure to save room for dessert—we recommend the flan.
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Arnaldo Richards' PicosPrice: Expensive• Regional Mexican• Upper Kirby / Shepherd Corridor
•
4.8
A
Anissa
Houston •3 reviews
5.0
Dined 3 days ago
Had team Christmas luncheon there. We had a great time
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Escalante's Fine Tex-Mex & Tequila - MeyerlandPrice: Moderate• Tex-Mex• Bellaire
•
4.6
N
Nam
Dallas - Fort Worth •5 reviews
5.0
Dined 5 days ago
It was very easy to reserve a table at Escalante’s through Open Table app. I appreciate the reminder ahead of time. Escalante’s offered a nice table in the corner and my friend and I had a nice visit. Great food!!! Our server provided excellent service. He was attentive and paid attention to detail. I am very happy with the experience. Thank you.
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Escalante's Fine Tex-Mex & Tequila - Town & CountryPrice: Moderate• Tex-Mex• Westside
•
4.6
A
Arsheen
Houston •1 review
5.0
Dined on Dec 6, 2024
The food was excellent, and the restaurant provides a quiet and pleasant atmosphere, making it a great spot to catch up with friends.
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Escalante's Fine Tex-Mex & Tequila - Highland VillagePrice: Moderate• Tex-Mex• River Oaks
•
4.8
OT
OpenTable DinerVIP
Houston •3 reviews
5.0
Dined on Dec 5, 2024
Mexican martini was amazing 🍸food is always good as well.
More info
Irma's SouthwestPrice: Expensive• Mexican / Southwestern• Downtown
•
4.6

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W. University / Med Center

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Best Southwest American Restaurants in W. University / Med Center

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184 restaurants available nearby

1. Drake's Hollywood - Houston

2. Milton's

3. Rosie Cannonball

4. Eunice

5. Clark's Oyster Bar - Houston

6. Balboa Surf Club

7. Leo's River Oaks

8. Hudson House - River Oaks

9. JOEY Uptown

10. Flora

See what locals rave about

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