Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. Denver / Colorado

Best Southwest American Restaurants in Downtown / LoDo

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Award-winning
Accessibility

143 restaurants available nearby

A photo of Church and Union - Denver restaurant
1. Church and Union - Denver
4.6
Exceptional(93)
Price: Expensive
• Mexican • Downtown / LoDo
Booked 26 times today
NOW OPEN! A 5th Street Group Concept | Modern-American cuisine served in a casual yet refined atmosphere with food by Top Chef Alum Jamie Lynch and Chef Partner Adam Hodgson. Brought to you by the team from Church and Union Charleston, Tempest Charleston, Church and Union Nashville, Ophelia's Pizza + Bar - Nashville, Church and Union Charlotte and La Belle Helene Charlotte. Church and Union Denver is located in the heart of Downtown Denver on 17th Street between Blake and Market Streets.
A photo of The Capital Grille - Denver restaurant
2. The Capital Grille - Denver
4.8
Exceptional(4744)
Price: Very Expensive
• Mexican • Downtown / LoDo
Booked 54 times today
Located in the heart of Downtown Denver, The Capital Grille is renowned not just for its expertly prepared steaks but also for its exceptional Wine Bar offerings. With over 350 selections meticulously curated, the venue boasts a floor-to-ceiling wine kiosk that houses between 3,500 to 5,000 bottles, promising an unmatched breadth and depth in wine choices. Patrons frequently laud the wine expertise provided, highlighting experiences such as those with Camilla, a trained sommelier, who offers spot-on wine and food pairings. Reviewers consistently praise the "exemplary service" and the "amazing lobster crab cakes and oysters," emphasizing that the Capital Grille in Denver stands out as a top-tier dining and wine destination.
A photo of Water Grill - Denver restaurant
3. Water Grill - Denver
4.6
Exceptional(1640)
Price: Expensive
• Mexican • Downtown / LoDo
Booked 46 times today
Water Grill - Denver, nestled in the vibrant LoDo neighborhood, offers a premier dining experience that transcends the typical seafood fare, even 1,000 miles from the nearest ocean. Renowned for its exceptional selection of fine cuts, the restaurant ensures the freshest seafood, with new arrivals several times a week. Patrons rave about the "delicious lobster roll, very tasty clam chowder, and a filet cooked to perfection," highlighting the impeccable quality and flavor. The changing daily menu, based on the freshest catch, consistently earns Water Grill accolades as one of Denver's top seafood destinations. As one reviewer puts it, "Perfect place for seafood in Denver. It was so fresh and the selection was outstanding." Whether for a special occasion or a delightful meal, Water Grill is the epitome of fine cuts cuisine in Denver.
A photo of Tamayo Restaurant restaurant
4. Tamayo Restaurant
4.4
Awesome(4395)
Price: Expensive
• Mexican • Downtown / LoDo
Booked 38 times today
At the heart of Denver's vibrant Downtown/Lodo district, Tamayo Restaurant sets the standard for exquisite Mexican cuisine. Helmed by the acclaimed Chef Richard Sandoval, known as the “Father of Modern Mexican Cuisine,” Tamayo offers a culinary adventure that is both authentic and innovative. With a menu that boasts savory dishes and an impressive selection of over 100 tequilas, guests consistently rave about their experiences. As one Mexican diner noted, the food is "exquisite," particularly recommending the "chicken tinga sopes and tacos." Whether it's the "amazing" bottomless brunch or the crafted cocktails like the serrano margarita, every visit to Tamayo promises a delightful and unforgettable dining experience, making it a must-visit for anyone seeking the true flavors of Mexico.
A photo of STK – Denver restaurant
5. STK – Denver
4.4
Awesome(3888)
Price: Expensive
• Mexican • Downtown / LoDo
Booked 81 times today
STK – Denver, nestled in the vibrant heart of Downtown LoDo, offers a unique twist on traditional American cuisine, blending classic dishes with modern flair. Described as "not your daddy’s steakhouse," this venue thrives with a high-energy atmosphere, complete with an in-house DJ and chic décor. Patrons rave about the "delicious and craveable steaks," emphasizing the quality and authenticity that STK prides itself on. Many guests highlight the exceptional service and unforgettable dining experiences, like the one who celebrated a special graduation, exclaiming, "the service was amazing with even better food!" Whether it's the upscale cocktails or the innovative menu with local nuances, STK – Denver delivers a top-tier American dining experience that consistently impresses, making it a must-visit destination for both locals and visitors alike.
A photo of BRUTØ restaurant
6. BRUTØ
new
4.8
Exceptional(28)
Price: Very Expensive
• Mexican • Downtown / LoDo
Booked 10 times today
The heart of BRUTØ lies in our hearth, a live fire sustained by oak wood and manned by our chefs from open to close each and every day. You’ll find that our menu is centered around brutalist ideas, curated thoughtfully and carefully in a way that encourages little to no waste between our tasting counter and our bar program. Our efforts in sustainable practices are showcased through our vast fermentation program and our commitment to locality by way of partnerships with our local farmers and ranchers. BRUTØ's intimate setting offers the opportunity to witness each and every step in the culinary process up close.BRUTØ is located inside of Free Market on the Dairy Block of downtown Denver. The dining room consists of an intimate chef's counter that faces into our open kitchen. Make a reservation to join us for our Chef's Tasting Menu Tuesday-Sunday evenings.
A photo of The Kitchen American Bistro - Denver restaurant
7. The Kitchen American Bistro - Denver
4.8
Exceptional(191)
Price: Expensive
• Mexican • Downtown / LoDo
Booked 36 times today
Nestled in the vibrant LoDo neighborhood of Denver, The Kitchen American Bistro shines as a beacon of American cuisine with a delightful twist. Praised for its “imaginative array of globally-inspired shared plates,” this eatery dazzles diners with its culinary creativity and exceptional service. Guests rave about the “killer drinks” and dishes like the burrata and crispy cauliflower, describing every bite as a “home run.” The atmosphere is described as stylish yet casual, perfect for any occasion, from a family dinner to a romantic evening. As one diner put it, “if I could give you two words of advice, they would be just go!” The Kitchen American Bistro is truly a must-visit for those seeking a top-tier dining experience in Denver.
A photo of The Corner Office Restaurant and Martini Bar Denver restaurant
8. The Corner Office Restaurant and Martini Bar Denver
4.2
Awesome(3690)
Price: Moderate
• Mexican • Downtown / LoDo
Booked 51 times today
Located in the vibrant heart of Downtown Denver, The Corner Office Restaurant and Martini Bar is a treasure trove of Contemporary American cuisine with a delightful twist. Known for its "progressive global comfort food," the restaurant offers a unique spin on traditional favorites, making each dish a fresh and exciting experience. Patrons rave about the diverse menu, highlighting the "delicious and creatively-prepared meals" that perfectly complement the energetic atmosphere. The restaurant is also celebrated for its exceptional service and "outstanding cocktails," particularly the martinis that are a hit among guests. Whether you're grabbing a bite before a show at the Denver Performing Arts Center or looking for a sumptuous brunch spot, The Corner Office promises a memorable dining experience with every visit.
A photo of Reynard Social restaurant
9. Reynard Social
4.8
Exceptional(10)
Price: Moderate
• Mexican • Downtown / LoDo
Booked 5 times today
Reynard Social is a lively lounge overlooking the Rocky Mountains, 16th Street Mall and the Denver skyline in the LoDo neighborhood. The name, Reynard, is a nod to the character of Reynard the Fox - the beloved trickster of European folklore whose mischievous nature and ingenious schemes never fail to topple the vain, the pompous and the crooked. He's a ne'er do well, a good-time fellow, a prankster, and an aristocrat. And, no matter how much hot water he gets himself into, he always lands on the side of the downtrodden. His story has been shared for centuries and endure to this day in many modern retellings. The experience and offerings celebrate the playfulness in all of us.
A photo of The Velvet Cellar restaurant
10. The Velvet Cellar
4.5
Awesome(214)
Price: Expensive
• Mexican • Denver
Booked 12 times today
The Velvet Cellar in Denver, located conveniently at the heart of the city near Union Station, is celebrated for its exceptional Bar / Lounge / Bottle Service. Patrons rave about the "fantastic wine selection" and the creatively crafted cocktails that are perfect for any occasion. With a "worldly wine flight mix," guests can taste a variety of superb wines, described in detail by the engaging staff, enhancing the overall dining experience. Reviews consistently highlight the welcoming atmosphere and the knowledgeable service, with one guest noting, "The owner stopped by our table with wines pouring directly from the bottles along with a concise description of each wine." This level of personal attention and the curated drink offerings make The Velvet Cellar a standout destination for those seeking a top-tier bar experience in Denver.

How is content generated

See what locals rave about

From verified diners like you
From verified diners like you

Discover best Mexican / Southwestern restaurants in Downtown / LoDo

Discover the vibrant flavors of Mexican cuisine right in the heart of Downtown Denver's LoDo district. This area is renowned for its diverse dining scene, where Mexican restaurants stand out by offering authentic dishes ranging from traditional moles to contemporary southwestern creations. Each restaurant in this district brings a unique twist to Mexican culinary traditions, ensuring that there is something to satisfy every palate. Customers can look forward to menus rich with options like hand-crafted margaritas, freshly made guacamole, and innovative dishes that showcase the deep culinary heritage of Mexico. The presence of over 100 tequilas at some establishments highlights the dedication to delivering a genuine Mexican dining experience. Reviews consistently praise the high-quality food, excellent service, and the lively atmosphere that define these eateries. Whether you're a local or a visitor, the Mexican restaurants in Downtown Denver's LoDo area promise an unforgettable dining experience that brilliantly captures the essence of Mexican culture and cuisine.

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Delight more diners
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo